Nicotinamide phosphoribosyltransferase postpones rat bone marrow mesenchymal stem cell senescence by mediating NAD(+)–Sirt1 signaling

In vitro replicative senescence affects MSC characteristics and functionality, thus severely restricting their application in regenerative medicine and MSC-based therapies. Previously, we found that MSC natural senescence is accompanied by altered intracellular nicotinamide adenine dinucleotide (NAD...

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Detalles Bibliográficos
Autores principales: Pi, Chenchen, Yang, Yue, Sun, Yanan, Wang, Huan, Sun, Hui, Ma, Mao, Lin, Lin, Shi, Yingai, Li, Yan, Li, Yulin, He, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594813/
https://www.ncbi.nlm.nih.gov/pubmed/31175267
http://dx.doi.org/10.18632/aging.101993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594813/
https://www.ncbi.nlm.nih.gov/pubmed/31175267
http://dx.doi.org/10.18632/aging.101993

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