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Nicotinamide phosphoribosyltransferase postpones rat bone marrow mesenchymal stem cell senescence by mediating NAD(+)–Sirt1 signaling

In vitro replicative senescence affects MSC characteristics and functionality, thus severely restricting their application in regenerative medicine and MSC-based therapies. Previously, we found that MSC natural senescence is accompanied by altered intracellular nicotinamide adenine dinucleotide (NAD...

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Detalles Bibliográficos
Autores principales:	Pi, Chenchen, Yang, Yue, Sun, Yanan, Wang, Huan, Sun, Hui, Ma, Mao, Lin, Lin, Shi, Yingai, Li, Yan, Li, Yulin, He, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594813/ https://www.ncbi.nlm.nih.gov/pubmed/31175267 http://dx.doi.org/10.18632/aging.101993

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