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TGF-β mediates aortic smooth muscle cell senescence in Marfan syndrome

Formation of aortic aneurysms as a consequence of augmented transforming growth factor β (TGF-β) signaling and vascular smooth muscle cell (VSMC) dysfunction is a potentially lethal complication of Marfan syndrome (MFS). Here, we examined VSMC senescence in patients with MFS and explored the potenti...

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Detalles Bibliográficos
Autores principales: You, Wei, Hong, Yimei, He, Haiwei, Huang, Xiaoran, Tao, Wuyuan, Liang, Xiaoting, Zhang, Yuelin, Li, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594817/
https://www.ncbi.nlm.nih.gov/pubmed/31147528
http://dx.doi.org/10.18632/aging.101998