Interleukin 6 receptor alpha expression in PMNs isolated from prematurely born neonates: Decreased expression is associated with differential mTOR signaling.

BACKGROUND: Dysregulated inflammation leads to morbidity and mortality in neonates. Neutrophil-mediated inflammation can cause inflammatory tissue damage. The mammalian Target of Rapamycin (mTOR) pathway governs IL-6Rα protein expression in human neutrophils. Shed IL-6Rα then participates in trans-s...

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Detalles Bibliográficos
Autores principales: Campbell, Robert A., Cody, Mark J., Manne, Bhanu K., Zimmerman, Guy A., Yost, Christian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594868/
https://www.ncbi.nlm.nih.gov/pubmed/30965356
http://dx.doi.org/10.1038/s41390-019-0388-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594868/
https://www.ncbi.nlm.nih.gov/pubmed/30965356
http://dx.doi.org/10.1038/s41390-019-0388-6

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