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Modulation of osteogenic and myogenic differentiation by a phytoestrogen formononetin via p38MAPK-dependent JAK-STAT and Smad-1/5/8 signaling pathways in mouse myogenic progenitor cells

Formononetin (FN), a typical phytoestrogen has attracted substantial attention as a novel agent because of its diverse biological activities including, osteogenic differentiation. However, the molecular mechanisms underlying osteogenic and myogenic differentiation by FN in C2C12 progenitor cells rem...

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Detalles Bibliográficos
Autores principales: Soundharrajan, Ilavenil, Kim, Da Hye, Kuppusamy, Palaniselvam, Choi, Ki Choon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594940/
https://www.ncbi.nlm.nih.gov/pubmed/31243298
http://dx.doi.org/10.1038/s41598-019-45793-w