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Adult Pgf(−/−) mice behaviour and neuroanatomy are altered by neonatal treatment with recombinant placental growth factor

Offspring of preeclamptic pregnancies have cognitive alterations. Placental growth factor (PGF), is low in preeclampsia; reduced levels may affect brain development. PGF-null mice differ from normal congenic controls in cerebrovasculature, neuroanatomy and behavior. Using brain imaging and behaviora...

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Detalles Bibliográficos
Autores principales: Kay, Vanessa R., Cahill, Lindsay S., Hanif, Anas, Sled, John G., Carmeliet, Peter, Tayade, Chandrakant, Croy, B. Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594955/
https://www.ncbi.nlm.nih.gov/pubmed/31243296
http://dx.doi.org/10.1038/s41598-019-45824-6