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Adult Pgf(−/−) mice behaviour and neuroanatomy are altered by neonatal treatment with recombinant placental growth factor
Offspring of preeclamptic pregnancies have cognitive alterations. Placental growth factor (PGF), is low in preeclampsia; reduced levels may affect brain development. PGF-null mice differ from normal congenic controls in cerebrovasculature, neuroanatomy and behavior. Using brain imaging and behaviora...
Autores principales: | Kay, Vanessa R., Cahill, Lindsay S., Hanif, Anas, Sled, John G., Carmeliet, Peter, Tayade, Chandrakant, Croy, B. Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594955/ https://www.ncbi.nlm.nih.gov/pubmed/31243296 http://dx.doi.org/10.1038/s41598-019-45824-6 |
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