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Noncoding dsRNA induces retinoic acid synthesis to stimulate hair follicle regeneration via TLR3

How developmental programs reactivate in regeneration is a fundamental question in biology. We addressed this question through the study of Wound Induced Hair follicle Neogenesis (WIHN), an adult organogenesis model where stem cells regenerate de novo hair follicles following deep wounding. The exac...

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Detalles Bibliográficos
Autores principales: Kim, Dongwon, Chen, Ruosi, Sheu, Mary, Kim, Noori, Kim, Sooah, Islam, Nasif, Wier, Eric M., Wang, Gaofeng, Li, Ang, Park, Angela, Son, Wooyang, Evans, Benjamin, Yu, Victoria, Prizmic, Vicky P., Oh, Eugene, Wang, Zixiao, Yu, Jianshi, Huang, Weiliang, Archer, Nathan K., Hu, Zhiqi, Clemetson, Nashay, Nelson, Amanda M., Chien, Anna, Okoye, Ginette A., Miller, Lloyd S., Ghiaur, Gabriel, Kang, Sewon, Jones, Jace W., Kane, Maureen A., Garza, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594970/
https://www.ncbi.nlm.nih.gov/pubmed/31243280
http://dx.doi.org/10.1038/s41467-019-10811-y