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Extracellular vesicles from human urine-derived stem cells prevent osteoporosis by transferring CTHRC1 and OPG

Osteoporosis is a debilitating bone disease affecting millions of people. Here, we used human urine-derived stem cells (USCs), which were noninvasively harvested from unlimited and easily available urine, as a “factory” to obtain extracellular vesicles (USC-EVs) and demonstrated that the systemic in...

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Detalles Bibliográficos
Autores principales: Chen, Chun-Yuan, Rao, Shan-Shan, Tan, Yi-Juan, Luo, Ming-Jie, Hu, Xiong-Ke, Yin, Hao, Huang, Jie, Hu, Yin, Luo, Zhong-Wei, Liu, Zheng-Zhao, Wang, Zhen-Xing, Cao, Jia, Liu, Yi-Wei, Li, Hong-Ming, Chen, Yang, Du, Wei, Liu, Jiang-Hua, Zhang, Yan, Chen, Tuan-Hui, Liu, Hao-Ming, Wu, Ben, Yue, Tao, Wang, Yi-Yi, Xia, Kun, Lei, Peng-Fei, Tang, Si-Yuan, Xie, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594995/
https://www.ncbi.nlm.nih.gov/pubmed/31263627
http://dx.doi.org/10.1038/s41413-019-0056-9