Cargando…

Extracellular vesicles from human urine-derived stem cells prevent osteoporosis by transferring CTHRC1 and OPG

Osteoporosis is a debilitating bone disease affecting millions of people. Here, we used human urine-derived stem cells (USCs), which were noninvasively harvested from unlimited and easily available urine, as a “factory” to obtain extracellular vesicles (USC-EVs) and demonstrated that the systemic in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Chun-Yuan, Rao, Shan-Shan, Tan, Yi-Juan, Luo, Ming-Jie, Hu, Xiong-Ke, Yin, Hao, Huang, Jie, Hu, Yin, Luo, Zhong-Wei, Liu, Zheng-Zhao, Wang, Zhen-Xing, Cao, Jia, Liu, Yi-Wei, Li, Hong-Ming, Chen, Yang, Du, Wei, Liu, Jiang-Hua, Zhang, Yan, Chen, Tuan-Hui, Liu, Hao-Ming, Wu, Ben, Yue, Tao, Wang, Yi-Yi, Xia, Kun, Lei, Peng-Fei, Tang, Si-Yuan, Xie, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594995/ https://www.ncbi.nlm.nih.gov/pubmed/31263627 http://dx.doi.org/10.1038/s41413-019-0056-9

Ejemplares similares

Exosomal DMBT1 from human urine-derived stem cells facilitates diabetic wound repair by promoting angiogenesis
por: Chen, Chun-Yuan, et al.
Publicado: (2018)

Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines
por: Rao, Shan-Shan, et al.
Publicado: (2018)

Synechococcus elongatus PCC7942 secretes extracellular vesicles to accelerate cutaneous wound healing by promoting angiogenesis
por: Yin, Hao, et al.
Publicado: (2019)

Extracellular Vesicles from Child Gut Microbiota Enter into Bone to Preserve Bone Mass and Strength
por: Liu, Jiang‐Hua, et al.
Publicado: (2021)

Ångstrom-scale silver particle–embedded carbomer gel promotes wound healing by inhibiting bacterial colonization and inflammation
por: Chen, Chun-Yuan, et al.
Publicado: (2020)

Glucocorticoid-induced loss of beneficial gut bacterial extracellular vesicles is associated with the pathogenesis of osteonecrosis
por: Chen, Chun-Yuan, et al.
Publicado: (2022)

The role of CTHRC1 in promotion of cutaneous wound healing
por: Duan, Xianlan, et al.
Publicado: (2022)

Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox
por: Wang, Zhen-Xing, et al.
Publicado: (2022)

Influence of DNA methylation on the expression of OPG/RANKL in primary osteoporosis
por: Wang, Peng, et al.
Publicado: (2018)

Delayed denervation-induced muscle atrophy in Opg knockout mice
por: Zhang, Mingming, et al.
Publicado: (2023)

Extracellular Vesicles from Akkermansia muciniphila Elicit Antitumor Immunity Against Prostate Cancer via Modulation of CD8(+) T Cells and Macrophages
por: Luo, Zhong-Wei, et al.
Publicado: (2021)

Establishment of OPG Transgenic Mice and the Effect of OPG on Bone Microarchitecture
por: Wu, Ying, et al.
Publicado: (2013)

Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimer's disease by enhancing autophagy
por: Chen, Meng-Lu, et al.
Publicado: (2021)

Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimer's disease by enhancing autophagy: Erratum
por: Chen, Meng-Lu, et al.
Publicado: (2021)

Fructose-coated Angstrom silver inhibits osteosarcoma growth and metastasis via promoting ROS-dependent apoptosis through the alteration of glucose metabolism by inhibiting PDK
por: Hu, Xiong-Ke, et al.
Publicado: (2020)

Fasting before or after wound injury accelerates wound healing through the activation of pro-angiogenic SMOC1 and SCG2
por: Luo, Ming-Jie, et al.
Publicado: (2020)

Human umbilical cord mesenchymal stromal cells-derived extracellular vesicles exert potent bone protective effects by CLEC11A-mediated regulation of bone metabolism
por: Hu, Yin, et al.
Publicado: (2020)

Fructose-coated Ångstrom silver prevents sepsis by killing bacteria and attenuating bacterial toxin-induced injuries
por: Yin, Hao, et al.
Publicado: (2021)

Overexpression of CTHRC1 in Hepatocellular Carcinoma Promotes Tumor Invasion and Predicts Poor Prognosis
por: Chen, Yu-Ling, et al.
Publicado: (2013)

Association between OPG polymorphisms and osteoporosis risk: An updated meta-analysis
por: Han, Xu, et al.
Publicado: (2022)

Neuronal Induction of Bone‐Fat Imbalance through Osteocyte Neuropeptide Y
por: Zhang, Yan, et al.
Publicado: (2021)

Exosomes from human umbilical cord blood accelerate cutaneous wound healing through miR-21-3p-mediated promotion of angiogenesis and fibroblast function
por: Hu, Yin, et al.
Publicado: (2018)

Harmine enhances type H vessel formation and prevents bone loss in ovariectomized mice
por: Huang, Jie, et al.
Publicado: (2018)

OPG rs2073617 polymorphism is associated with upregulated OPG protein expression and an increased risk of intervertebral disc degeneration
por: Xue, Jing-Bo, et al.
Publicado: (2016)

Extracellular Vesicles from Human Urine-Derived Stem Cells Ameliorate Particulate Polyethylene-Induced Osteolysis
por: Li, Hui, et al.
Publicado: (2021)

Diagnostic accuracy of loop-mediated isothermal amplification in detection of Clostridium difficile in stool samples: a meta-analysis
por: Wei, Chen, et al.
Publicado: (2015)

Mechanical force regulates root resorption in rats through RANKL and OPG
por: Zhou, Jianli, et al.
Publicado: (2022)

Acupotomy Contributes to Suppressing Subchondral Bone Resorption in KOA Rabbits by Regulating the OPG/RANKL Signaling Pathway
por: Wang, Tong, et al.
Publicado: (2021)

Identification of hub genes associated with postmenopausal osteoporosis by Gibbs sampling method
por: Zhang, Ya-Peng, et al.
Publicado: (2019)

Baicalin Ameliorates Dexamethasone-Induced Osteoporosis by Regulation of the RANK/RANKL/OPG Signaling Pathway
por: Zhao, Ye, et al.
Publicado: (2020)

CTHRC1 May Serve As A Prognostic Biomarker For Hepatocellular Carcinoma
por: Zhou, Huifang, et al.
Publicado: (2019)

Targeting the RANKL/RANK/OPG Axis for Cancer Therapy
por: Ming, Jie, et al.
Publicado: (2020)

The Protective Effects of Osteocyte‐Derived Extracellular Vesicles Against Alzheimer's Disease Diminished with Aging
por: Jiang, Ya‐Ling, et al.
Publicado: (2022)

Chondroitin Sulfate Prevents STZ Induced Diabetic Osteoporosis through Decreasing Blood Glucose, AntiOxidative Stress, Anti-Inflammation and OPG/RANKL Expression Regulation
por: Zheng, Hong Xing, et al.
Publicado: (2020)

Weaning from venous-arterial extracorporeal membrane oxygenation: The hemodynamic and clinical aspects of flow challenge test
por: Luo, Jing-chao, et al.
Publicado: (2022)

A Prognostic Signature Constructed by CTHRC1 and LRFN4 in Stomach Adenocarcinoma
por: Han, Songling, et al.
Publicado: (2021)

The Influence of Aggressive Parenteral Nutrition to Preterm and Very Low Birth Weight Infants
por: Liu, Ming-Yi, et al.
Publicado: (2015)

Metformin accelerates bone fracture healing by promoting type H vessel formation through inhibition of YAP1/TAZ expression
por: Ruan, Zhe, et al.
Publicado: (2023)

CTHRC1 and PD-1/PD-L1 expression predicts tumor recurrence in prostate cancer
por: Zhou, Qing, et al.
Publicado: (2019)

MITA oligomerization upon viral infection is dependent on its N-glycosylation mediated by DDOST
por: Tu, Yi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_sruh0fd1vt6d4ncrg2k5qephu4