Insights into real-time chemical processes in a calcium sensor protein-directed dynamic library

Dynamic combinatorial chemistry (DCC) has proven its potential in drug discovery speeding the identification of modulators of biological targets. However, the exchange chemistries typically take place under specific reaction conditions, with limited tools capable of operating under physiological par...

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Detalles Bibliográficos
Autores principales: Canal-Martín, Andrea, Sastre, Javier, Sánchez-Barrena, María José, Canales, Angeles, Baldominos, Sara, Pascual, Naiara, Martínez-González, Loreto, Molero, Dolores, Fernández-Valle, Mª Encarnación, Sáez, Elena, Blanco-Gabella, Patricia, Gómez-Rubio, Elena, Martín-Santamaría, Sonsoles, Sáiz, Almudena, Mansilla, Alicia, Cañada, F. Javier, Jiménez-Barbero, Jesús, Martínez, Ana, Pérez-Fernández, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595003/
https://www.ncbi.nlm.nih.gov/pubmed/31243268
http://dx.doi.org/10.1038/s41467-019-10627-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595003/
https://www.ncbi.nlm.nih.gov/pubmed/31243268
http://dx.doi.org/10.1038/s41467-019-10627-w

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