Structural basis for cooperativity of human monoclonal antibodies to meningococcal factor H-binding protein

Monoclonal antibody (mAb) cooperativity is a phenomenon triggered when mAbs couples promote increased bactericidal killing compared to individual partners. Cooperativity has been deeply investigated among mAbs elicited by factor H-binding protein (fHbp), a Neisseria meningitidis surface-exposed lipo...

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Detalles Bibliográficos
Autores principales: Peschiera, Ilaria, Giuliani, Maria, Giusti, Fabiola, Melero, Roberto, Paccagnini, Eugenio, Donnarumma, Danilo, Pansegrau, Werner, Carazo, José M., Sorzano, Carlos O. S., Scarselli, Maria, Masignani, Vega, Liljeroos, Lassi J., Ferlenghi, Ilaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595007/
https://www.ncbi.nlm.nih.gov/pubmed/31263785
http://dx.doi.org/10.1038/s42003-019-0493-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595007/
https://www.ncbi.nlm.nih.gov/pubmed/31263785
http://dx.doi.org/10.1038/s42003-019-0493-4

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