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Effects of biomarker diagnostic accuracy on biomarker-guided phase 2 trials

Recent advancements in genomics have attracted attention towards biomarker-guided trials. These trials aim to identify therapies that target diseases based on their genetic profile, and are especially common in cancer research. Careful incorporation of biomarkers in phase II studies is critical to t...

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Detalles Bibliográficos
Autores principales: Park, Jay JH., Harari, Ofir, Dron, Louis, Mills, Edward J., Thorlund, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595080/
https://www.ncbi.nlm.nih.gov/pubmed/31294127
http://dx.doi.org/10.1016/j.conctc.2019.100396