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Effects of biomarker diagnostic accuracy on biomarker-guided phase 2 trials
Recent advancements in genomics have attracted attention towards biomarker-guided trials. These trials aim to identify therapies that target diseases based on their genetic profile, and are especially common in cancer research. Careful incorporation of biomarkers in phase II studies is critical to t...
Autores principales: | Park, Jay JH., Harari, Ofir, Dron, Louis, Mills, Edward J., Thorlund, Kristian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595080/ https://www.ncbi.nlm.nih.gov/pubmed/31294127 http://dx.doi.org/10.1016/j.conctc.2019.100396 |
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