Cargando…

Endless Forms: Within-Host Variation in the Structure of the West Nile Virus RNA Genome during Serial Passage in Bird Hosts

RNA viruses are infamous for their high rates of mutation, which produce swarms of genetic variants within individual hosts. To date, analyses of intrahost genetic diversity have focused on the primary genome sequence. However, virus phenotypes are shaped not only by primary sequence but also by the...

Descripción completa

Detalles Bibliográficos
Autores principales: Scroggs, Stacey L. P., Grubaugh, Nathan D., Sena, Johnny A., Sundararajan, Anitha, Schilkey, Faye D., Smith, Darci R., Ebel, Gregory D., Hanley, Kathryn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595145/
https://www.ncbi.nlm.nih.gov/pubmed/31243074
http://dx.doi.org/10.1128/mSphere.00291-19