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Endless Forms: Within-Host Variation in the Structure of the West Nile Virus RNA Genome during Serial Passage in Bird Hosts
RNA viruses are infamous for their high rates of mutation, which produce swarms of genetic variants within individual hosts. To date, analyses of intrahost genetic diversity have focused on the primary genome sequence. However, virus phenotypes are shaped not only by primary sequence but also by the...
Autores principales: | Scroggs, Stacey L. P., Grubaugh, Nathan D., Sena, Johnny A., Sundararajan, Anitha, Schilkey, Faye D., Smith, Darci R., Ebel, Gregory D., Hanley, Kathryn A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595145/ https://www.ncbi.nlm.nih.gov/pubmed/31243074 http://dx.doi.org/10.1128/mSphere.00291-19 |
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