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Expression of precipitating factors of pruritus found in humans in an imiquimod-induced psoriasis mouse model

AIMS: To use a mouse model of imiquimod-induced psoriasis to investigate the relationship between pruritus and mast cells, nerve growth factor (NGF) and endogenous pruritogenic peptides, which are highly expressed in the skin of psoriasis patients. MAIN METHODS: We developed a mouse model of imiquim...

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Detalles Bibliográficos
Autores principales: Oishi, Nobuo, Iwata, Hiroki, Kambe, Naotomo, Kobayashi, Noriko, Fujimoto, Kazuko, Sato, Hiromi, Hisaka, Akihiro, Ueno, Koichi, Yamaura, Katsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595246/
https://www.ncbi.nlm.nih.gov/pubmed/31294123
http://dx.doi.org/10.1016/j.heliyon.2019.e01981