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Adverse immunostimulation caused by impurities: The dark side of biopharmaceuticals

Drug safety is an important issue, especially in the experimental phases of development. Adverse immunostimulation (AI) is sometimes encountered following treatment with biopharmaceuticals, which can be life‐threatening if it results in a severe systemic inflammatory reaction. Biopharmaceuticals tha...

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Detalles Bibliográficos
Autores principales: Reijers, Joannes A. A., Malone, Karen E., Bajramovic, Jeffrey J., Verbeek, Richard, Burggraaf, Jacobus, Moerland, Matthijs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595286/
https://www.ncbi.nlm.nih.gov/pubmed/30920013
http://dx.doi.org/10.1111/bcp.13938