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Association of PON1 gene promoter DNA methylation with the risk of Clopidogrel resistance in patients with coronary artery disease

BACKGROUND AND AIMS: The failure of therapeutic response to clopidogrel in platelet inhibition, which is called clopidogrel resistance (CR), is more likely to cause cardiovascular events. We aimed to study the contribution of promoter DNA methylation of paraoxonase 1 (PON1) to the risk of clopidogre...

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Detalles Bibliográficos
Autores principales: Su, Jia, Li, Jiyi, Yu, Qinglin, Xu, Xiaofeng, Wang, Jingqiao, Yang, Jin, Li, Xiaojing, Chen, Xiaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595294/
https://www.ncbi.nlm.nih.gov/pubmed/30891852
http://dx.doi.org/10.1002/jcla.22867