Caffeine boosts Ataluren's readthrough activity

The readthrough of nonsense mutations by small molecules like Ataluren is considered a novel therapeutic approach to overcome the gene defect in several genetic diseases as cystic fibrosis (CF). This pharmacological approach suppresses translation termination at premature termination codons (PTCs re...

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Detalles Bibliográficos
Autores principales: Lentini, Laura, Melfi, Raffaella, Cancemi, Patrizia, Pibiri, Ivana, Di Leonardo, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595402/
https://www.ncbi.nlm.nih.gov/pubmed/31294114
http://dx.doi.org/10.1016/j.heliyon.2019.e01963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595402/
https://www.ncbi.nlm.nih.gov/pubmed/31294114
http://dx.doi.org/10.1016/j.heliyon.2019.e01963

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