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Nociceptor Deletion of Tsc2 Enhances Axon Regeneration by Inducing a Conditioning Injury Response in Dorsal Root Ganglia

Neurons of the PNS are able to regenerate injured axons, a process requiring significant cellular resources to establish and maintain long-distance growth. Genetic activation of mTORC1, a potent regulator of cellular metabolism and protein translation, improves axon regeneration of peripheral neuron...

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Detalles Bibliográficos
Autores principales: Carlin, Dan, Halevi, Alexandra E., Ewan, Eric E., Moore, Amy M., Cavalli, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595439/
https://www.ncbi.nlm.nih.gov/pubmed/31182472
http://dx.doi.org/10.1523/ENEURO.0168-19.2019