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Commonly integrated epigenetic modifications of differentially expressed genes lead to adaptive resistance in cancer

AIM: To investigate the integrated epigenetic regulation of acquired drug resistance in cancer. MATERIALS & METHODS: Our gene expression data of five induced drug-tolerant cell models, one resistant cell line and one publicly available drug-resistant dataset were integrated to identify common di...

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Detalles Bibliográficos
Autores principales: Emran, Abdullah Al, Marzese, Diego M, Menon, Dinoop R, Hammerlindl, Heinz, Ahmed, Farzana, Richtig, Erika, Duijf, Pascal, Hoon, Dave SB, Schaider, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595545/
https://www.ncbi.nlm.nih.gov/pubmed/31070054
http://dx.doi.org/10.2217/epi-2018-0173