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Commonly integrated epigenetic modifications of differentially expressed genes lead to adaptive resistance in cancer
AIM: To investigate the integrated epigenetic regulation of acquired drug resistance in cancer. MATERIALS & METHODS: Our gene expression data of five induced drug-tolerant cell models, one resistant cell line and one publicly available drug-resistant dataset were integrated to identify common di...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Medicine Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595545/ https://www.ncbi.nlm.nih.gov/pubmed/31070054 http://dx.doi.org/10.2217/epi-2018-0173 |