Family-specific genotype arrays increase the accuracy of pedigree-based imputation at very low marker densities

BACKGROUND: In this paper, we evaluate the performance of using family-specific low-density genotype arrays to increase the accuracy of pedigree-based imputation. Genotype imputation is a widely used tool that decreases the costs of genotyping a population by genotyping the majority of individuals o...

Descripción completa

Detalles Bibliográficos
Autores principales: Whalen, Andrew, Gorjanc, Gregor, Hickey, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595555/
https://www.ncbi.nlm.nih.gov/pubmed/31242856
http://dx.doi.org/10.1186/s12711-019-0478-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595555/
https://www.ncbi.nlm.nih.gov/pubmed/31242856
http://dx.doi.org/10.1186/s12711-019-0478-2

Ejemplares similares