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Pre-clinical investigation of the synergy effect of interleukin-12 gene-electro-transfer during partially irreversible electropermeabilization against melanoma

BACKGROUND: Melanoma is a very aggressive skin tumor that can be cured when diagnosed and treated in its early stages. However, at the time of identification, the tumor is frequently in a metastatic stage. Intensive research is currently ongoing to improve the efficacy of the immune system in elimin...

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Detalles Bibliográficos
Autores principales: Pasquet, Lise, Bellard, Elisabeth, Chabot, Sophie, Markelc, Bostjan, Rols, Marie-Pierre, Teissie, Justin, Golzio, Muriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595571/
https://www.ncbi.nlm.nih.gov/pubmed/31242938
http://dx.doi.org/10.1186/s40425-019-0638-5