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Parent-of-origin-specific allelic expression in the human placenta is limited to established imprinted loci and it is stably maintained across pregnancy

BACKGROUND: Genomic imprinting, mediated by parent-of-origin-specific epigenetic silencing, adjusts the gene expression dosage in mammals. We aimed to clarify parental allelic expression in the human placenta for 396 claimed candidate imprinted genes and to assess the evidence for the proposed enric...

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Detalles Bibliográficos
Autores principales: Pilvar, Diana, Reiman, Mario, Pilvar, Arno, Laan, Maris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595585/
https://www.ncbi.nlm.nih.gov/pubmed/31242935
http://dx.doi.org/10.1186/s13148-019-0692-3