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Costunolide induces mitochondria-mediated apoptosis in human gastric adenocarcinoma BGC-823 cells

BACKGROUND: Costunolide, a sesquiterpene lactone extracted from Radix Aucklandiae, has the activity against multiple cancers. However, the effect of costunolide on gastric cancer (GC) have remained to be ambiguous. In this study, we investigated the underlying mechanisms of apoptosis induced by cost...

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Detalles Bibliográficos
Autores principales: Yan, Zhanpeng, Xu, Tingting, An, Zhentao, Hu, Ying, Chen, Wanzhen, Ma, Jinxia, Shao, Changle, Zhu, Fangshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595696/
https://www.ncbi.nlm.nih.gov/pubmed/31242894
http://dx.doi.org/10.1186/s12906-019-2569-6