Activated mTOR signaling pathway in myofibers with inherited metabolic defect might be an evidence for mTOR inhibition therapies

BACKGROUND: Abnormally activated mechanistic target of rapamycin (mTOR) pathway has been reported in several model animals with inherited metabolic myopathies (IMMs). However, the profiles of mTOR pathway in skeletal muscles from patients are still unknown. This study aimed to analyze the activity o...

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Detalles Bibliográficos
Autores principales: Lyu, Jing-Wei, Xu, Xue-Bi, Ji, Kun-Qian, Zhang, Na, Sun, Yuan, Zhao, Dan-Dan, Zhao, Yu-Ying, Yan, Chuan-Zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595864/
https://www.ncbi.nlm.nih.gov/pubmed/30897595
http://dx.doi.org/10.1097/CM9.0000000000000144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595864/
https://www.ncbi.nlm.nih.gov/pubmed/30897595
http://dx.doi.org/10.1097/CM9.0000000000000144

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