Spinal Interleukin-1β Inhibits Astrocyte Cytochrome P450c17 Expression Which Controls the Development of Mechanical Allodynia in a Mouse Model of Neuropathic Pain

We have recently demonstrated that sciatic nerve injury increases the expression of spinal cytochrome P450c17, a key neurosteroidogenic enzyme, which plays a critical role in the development of peripheral neuropathic pain. However, the modulatory mechanisms responsible for the expression of spinal P...

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Detalles Bibliográficos
Autores principales: Choi, Sheu-Ran, Han, Ho-Jae, Beitz, Alvin J., Lee, Jang-Hern
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596369/
https://www.ncbi.nlm.nih.gov/pubmed/31281242
http://dx.doi.org/10.3389/fnmol.2019.00153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596369/
https://www.ncbi.nlm.nih.gov/pubmed/31281242
http://dx.doi.org/10.3389/fnmol.2019.00153

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