Pair Matcher (PaM): fast model-based optimization of treatment/case-control matches

MOTIVATION: In clinical trials, individuals are matched using demographic criteria, paired and then randomly assigned to treatment and control groups to determine a drug’s efficacy. A chief cause for the irreproducibility of results across pilot to Phase-III trials is population stratification bias...

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Detalles Bibliográficos
Autores principales: Elhaik, Eran, Ryan, Desmond M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596890/
https://www.ncbi.nlm.nih.gov/pubmed/30445488
http://dx.doi.org/10.1093/bioinformatics/bty946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596890/
https://www.ncbi.nlm.nih.gov/pubmed/30445488
http://dx.doi.org/10.1093/bioinformatics/bty946

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