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Pair Matcher (PaM): fast model-based optimization of treatment/case-control matches
MOTIVATION: In clinical trials, individuals are matched using demographic criteria, paired and then randomly assigned to treatment and control groups to determine a drug’s efficacy. A chief cause for the irreproducibility of results across pilot to Phase-III trials is population stratification bias...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596890/ https://www.ncbi.nlm.nih.gov/pubmed/30445488 http://dx.doi.org/10.1093/bioinformatics/bty946 |