pyNVR: investigating factors affecting feature selection from scRNA-seq data for lineage reconstruction

MOTIVATION: The emergence of single-cell RNA-sequencing has enabled analyses that leverage transitioning cell states to reconstruct pseudotemporal trajectories. Multidimensional data sparsity, zero inflation and technical variation necessitate the selection of high-quality features that feed downstr...

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Detalles Bibliográficos
Autores principales: Chen, Bob, Herring, Charles A, Lau, Ken S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596893/
https://www.ncbi.nlm.nih.gov/pubmed/30445607
http://dx.doi.org/10.1093/bioinformatics/bty950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596893/
https://www.ncbi.nlm.nih.gov/pubmed/30445607
http://dx.doi.org/10.1093/bioinformatics/bty950

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