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pyNVR: investigating factors affecting feature selection from scRNA-seq data for lineage reconstruction
MOTIVATION: The emergence of single-cell RNA-sequencing has enabled analyses that leverage transitioning cell states to reconstruct pseudotemporal trajectories. Multidimensional data sparsity, zero inflation and technical variation necessitate the selection of high-quality features that feed downstr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596893/ https://www.ncbi.nlm.nih.gov/pubmed/30445607 http://dx.doi.org/10.1093/bioinformatics/bty950 |