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4E‐BP1 and 4E‐BP2 double knockout mice are protected from aging‐associated sarcopenia

BACKGROUND: Sarcopenia is the loss of muscle mass/function that occurs during the aging process. The links between mechanistic target of rapamycin (mTOR) activity and muscle development are largely documented, but the role of its downstream targets in the development of sarcopenia is poorly understo...

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Detalles Bibliográficos
Autores principales: Le Bacquer, Olivier, Combe, Kristell, Patrac, Véronique, Ingram, Brian, Combaret, Lydie, Dardevet, Dominique, Montaurier, Christophe, Salles, Jérôme, Giraudet, Christophe, Guillet, Christelle, Sonenberg, Nahum, Boirie, Yves, Walrand, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596930/
https://www.ncbi.nlm.nih.gov/pubmed/30927336
http://dx.doi.org/10.1002/jcsm.12412