A Conserved PLPLRT/SD Motif of STING Mediates the Recruitment and Activation of TBK1

Nucleic acids from bacteria or viruses induce potent immune responses in infected cells(1–4). The detection of pathogen-derived nucleic acids is a central strategy by which the host senses infection and initiates protective immune responses(5,6). Cyclic GMP-AMP synthase (cGAS) is a double-stranded D...

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Detalles Bibliográficos
Autores principales: Zhao, Baoyu, Du, Fenglei, Xu, Pengbiao, Shu, Chang, Sankaran, Banumathi, Bell, Samantha L., Liu, Mengmeng, Lei, Yuanjiu, Gao, Xinsheng, Fu, Xiaofeng, Zhu, Fanxiu, Liu, Yang, Laganowsky, Arthur D., Zheng, Xueyun, Ji, Junyuan, West, A. Philip, Watson, Robert O., Li, Pingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596994/
https://www.ncbi.nlm.nih.gov/pubmed/31118511
http://dx.doi.org/10.1038/s41586-019-1228-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596994/
https://www.ncbi.nlm.nih.gov/pubmed/31118511
http://dx.doi.org/10.1038/s41586-019-1228-x

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