Tumor M2-PK: A novel urine marker of bladder cancer

PURPOSE: Bladder cancer is a “Warburg-like” tumor characterized by a reliance on aerobic glycolysis and expression of pyruvate kinase M2 (PKM2). PKM2 oscillates between an active tetramer and an inactive dimer. We aim to further characterize PKM2, in particular PKM2 dimer, as a urinary biomarker of...

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Detalles Bibliográficos
Autores principales: Liu, Weiya, Woolbright, Benjamin L., Pirani, Karim, Didde, Ryan, Abbott, Erika, Kaushik, Gaurav, Martin, Paige, Hamilton-Reeves, Jill, Taylor, John A., Holzbeierlein, Jeffrey M., Anant, Shrikant, Lee, Eugene K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597081/
https://www.ncbi.nlm.nih.gov/pubmed/31246990
http://dx.doi.org/10.1371/journal.pone.0218737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597081/
https://www.ncbi.nlm.nih.gov/pubmed/31246990
http://dx.doi.org/10.1371/journal.pone.0218737

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