miR-19 targets PTEN and mediates high mobility group protein B1(HMGB1)-induced proliferation and migration of human airway smooth muscle cells

BACKGROUND: The abnormal proliferation and migration of airway smooth muscle (ASM) cells contributes to airway remodeling during asthma. MiR-19a has been demonstrated to promote cell proliferation and angiogenesis of several cancer types by regulating the PTEN/PI3K/AKT pathway. Our previous study ha...

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Detalles Bibliográficos
Autores principales: Hou, Changchun, Chen, Yan, Huang, Xiaolin, Huang, Qinghua, Li, Mengze, Tan, Xiaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597099/
https://www.ncbi.nlm.nih.gov/pubmed/31247032
http://dx.doi.org/10.1371/journal.pone.0219081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597099/
https://www.ncbi.nlm.nih.gov/pubmed/31247032
http://dx.doi.org/10.1371/journal.pone.0219081

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