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Response to comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'

In 2016, we reported four substantial observations of APECED/APS1 patients, who are deficient in AIRE, a major regulator of central T cell tolerance (Meyer et al., 2016). Two of those observations have been challenged. Specifically, ‘private’ autoantibody reactivities shared by only a few patients b...

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Detalles Bibliográficos
Autores principales: Hertel, Christina, Fishman, Dmytro, Lorenc, Anna, Ranki, Annamari, Krohn, Kai, Peterson, Pärt, Kisand, Kai, Hayday, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597236/
https://www.ncbi.nlm.nih.gov/pubmed/31244472
http://dx.doi.org/10.7554/eLife.45826