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Below the surface: The inner lives of TLR4 and TLR9

TLRs are a class of pattern recognition receptors (PRRs) that detect invading microbes by recognizing pathogen‐associated molecular patterns (PAMPs). Upon PAMP engagement, TLRs activate a signaling cascade that leads to the production of inflammatory mediators. The localization of TLRs, either on th...

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Detalles Bibliográficos
Autores principales: Marongiu, Laura, Gornati, Laura, Artuso, Irene, Zanoni, Ivan, Granucci, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597292/
https://www.ncbi.nlm.nih.gov/pubmed/30900780
http://dx.doi.org/10.1002/JLB.3MIR1218-483RR