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Poorly-Controlled Type 1 Diabetes Mellitus Impairs LH-LHCGR Signaling in the Ovaries and Decreases Female Fertility in Mice

PURPOSE: The aim of this study was to investigate how type I diabetes mellitus (T1D) affects the folliculogenesis and oocyte development, fertilization, and embryo development. MATERIALS AND METHODS: A comparative animal study was conducted using two different mouse models of T1D, a genetic AKITA mo...

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Detalles Bibliográficos
Autores principales: Lee, Jaewang, Lee, Hoi Chang, Kim, So-Youn, Cho, Geum Joon, Woodruff, Teresa K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597468/
https://www.ncbi.nlm.nih.gov/pubmed/31250581
http://dx.doi.org/10.3349/ymj.2019.60.7.667