STING induces early IFN-β in the liver and constrains myeloid cell-mediated dissemination of murine cytomegalovirus

Cytomegalovirus is a DNA-encoded β-herpesvirus that induces STING-dependent type 1 interferon responses in macrophages and uses myeloid cells as a vehicle for dissemination. Here we report that STING knockout mice are as resistant to murine cytomegalovirus (MCMV) infection as wild-type controls, whe...

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Detalles Bibliográficos
Autores principales: Tegtmeyer, Pia-Katharina, Spanier, Julia, Borst, Katharina, Becker, Jennifer, Riedl, André, Hirche, Christoph, Ghita, Luca, Skerra, Jennifer, Baumann, Kira, Lienenklaus, Stefan, Doering, Marius, Ruzsics, Zsolt, Kalinke, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597531/
https://www.ncbi.nlm.nih.gov/pubmed/31249303
http://dx.doi.org/10.1038/s41467-019-10863-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597531/
https://www.ncbi.nlm.nih.gov/pubmed/31249303
http://dx.doi.org/10.1038/s41467-019-10863-0

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