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ABCB1 protects bat cells from DNA damage induced by genotoxic compounds

Bats are unusual mammals, with the ability to fly, and long lifespans. In addition, bats have a low incidence of cancer, but the mechanisms underlying this phenomenon remain elusive. Here we discovered that bat cells are more resistant than human and mouse cells to DNA damage induced by genotoxic dr...

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Detalles Bibliográficos
Autores principales: Koh, Javier, Itahana, Yoko, Mendenhall, Ian H., Low, Dolyce, Soh, Eunice Xin Yi, Guo, Alvin Kunyao, Chionh, Yok Teng, Wang, Lin-Fa, Itahana, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597548/
https://www.ncbi.nlm.nih.gov/pubmed/31249297
http://dx.doi.org/10.1038/s41467-019-10495-4