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Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes

Sufficient vascular supply is indispensable for brain development and function, whereas dysfunctional blood vessels are associated with human diseases such as vascular malformations, stroke or neurodegeneration. Pericytes are capillary-associated mesenchymal cells that limit vascular permeability an...

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Detalles Bibliográficos
Autores principales: Diéguez-Hurtado, Rodrigo, Kato, Katsuhiro, Giaimo, Benedetto Daniele, Nieminen-Kelhä, Melina, Arf, Hendrik, Ferrante, Francesca, Bartkuhn, Marek, Zimmermann, Tobias, Bixel, M. Gabriele, Eilken, Hanna M., Adams, Susanne, Borggrefe, Tilman, Vajkoczy, Peter, Adams, Ralf H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597568/
https://www.ncbi.nlm.nih.gov/pubmed/31249304
http://dx.doi.org/10.1038/s41467-019-10643-w