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Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes
Sufficient vascular supply is indispensable for brain development and function, whereas dysfunctional blood vessels are associated with human diseases such as vascular malformations, stroke or neurodegeneration. Pericytes are capillary-associated mesenchymal cells that limit vascular permeability an...
Autores principales: | Diéguez-Hurtado, Rodrigo, Kato, Katsuhiro, Giaimo, Benedetto Daniele, Nieminen-Kelhä, Melina, Arf, Hendrik, Ferrante, Francesca, Bartkuhn, Marek, Zimmermann, Tobias, Bixel, M. Gabriele, Eilken, Hanna M., Adams, Susanne, Borggrefe, Tilman, Vajkoczy, Peter, Adams, Ralf H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597568/ https://www.ncbi.nlm.nih.gov/pubmed/31249304 http://dx.doi.org/10.1038/s41467-019-10643-w |
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