Tremorgenic effects and functional metabolomics analysis of lolitrem B and its biosynthetic intermediates

The neuroactive mycotoxin lolitrem B causes a neurological syndrome in grazing livestock resulting in hyperexcitability, muscle tremors, ataxia and, in severe cases, clonic seizures and death. To define the effects of the major toxin lolitrem B in the brain, a functional metabolomic study was undert...

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Detalles Bibliográficos
Autores principales: Reddy, Priyanka, Rochfort, Simone, Read, Elizabeth, Deseo, Myrna, Jaehne, Emily, Van Den Buuse, Maarten, Guthridge, Kathryn, Combs, Martin, Spangenberg, German, Quinn, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597573/
https://www.ncbi.nlm.nih.gov/pubmed/31249318
http://dx.doi.org/10.1038/s41598-019-45170-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597573/
https://www.ncbi.nlm.nih.gov/pubmed/31249318
http://dx.doi.org/10.1038/s41598-019-45170-7

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