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Quantitative single-cell live imaging links HES5 dynamics with cell-state and fate in murine neurogenesis
During embryogenesis cells make fate decisions within complex tissue environments. The levels and dynamics of transcription factor expression regulate these decisions. Here, we use single cell live imaging of an endogenous HES5 reporter and absolute protein quantification to gain a dynamic view of n...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597611/ https://www.ncbi.nlm.nih.gov/pubmed/31249377 http://dx.doi.org/10.1038/s41467-019-10734-8 |