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Quantitative single-cell live imaging links HES5 dynamics with cell-state and fate in murine neurogenesis

During embryogenesis cells make fate decisions within complex tissue environments. The levels and dynamics of transcription factor expression regulate these decisions. Here, we use single cell live imaging of an endogenous HES5 reporter and absolute protein quantification to gain a dynamic view of n...

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Detalles Bibliográficos
Autores principales:	Manning, Cerys S., Biga, Veronica, Boyd, James, Kursawe, Jochen, Ymisson, Bodvar, Spiller, David G., Sanderson, Christopher M., Galla, Tobias, Rattray, Magnus, Papalopulu, Nancy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597611/ https://www.ncbi.nlm.nih.gov/pubmed/31249377 http://dx.doi.org/10.1038/s41467-019-10734-8

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