Neuregulin-1β Partially Improves Cardiac Function in Volume-Overload Heart Failure Through Regulation of Abnormal Calcium Handling

Background: Neuregulin (NRG-1), an essential stress-mediated paracrine growth factor, has a cardioprotective effect in failing heart. However, the underlying mechanism remains unclear. The role of NRG-1β in heart failure (HF) rats was examined. Methods and Results: Volume-overload HF rat model was c...

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Detalles Bibliográficos
Autores principales: Wang, Xuehui, Zhuo, Xiaozhen, Gao, Jie, Liu, Huibing, Lin, Fei, Ma, Aiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597678/
https://www.ncbi.nlm.nih.gov/pubmed/31281251
http://dx.doi.org/10.3389/fphar.2019.00616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597678/
https://www.ncbi.nlm.nih.gov/pubmed/31281251
http://dx.doi.org/10.3389/fphar.2019.00616

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