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Wnt signalling mediates miR-133a nuclear re-localization for the transcriptional control of Dnmt3b in cardiac cells

MiR-133a is a muscle-enriched miRNA, which plays a key role for proper skeletal and cardiac muscle function via regulation of transduction cascades, including the Wnt signalling. MiR-133a modulates its targets via canonical mRNA repression, a process that has been largely demonstrated to occur withi...

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Detalles Bibliográficos
Autores principales: Di Mauro, Vittoria, Crasto, Silvia, Colombo, Federico Simone, Di Pasquale, Elisa, Catalucci, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597717/
https://www.ncbi.nlm.nih.gov/pubmed/31249372
http://dx.doi.org/10.1038/s41598-019-45818-4