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Characterisation of a solvent-tolerant haloarchaeal (R)-selective transaminase isolated from a Triassic period salt mine

Transaminase enzymes (TAms) are becoming increasingly valuable in the chemist’s toolbox as a biocatalytic route to chiral amines. Despite high profile successes, the lack of (R)-selective TAms and robustness under harsh industrial conditions continue to prove problematic. Herein, we report the isola...

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Detalles Bibliográficos
Autores principales: Kelly, Stephen A., Magill, Damian J., Megaw, Julianne, Skvortsov, Timofey, Allers, Thorsten, McGrath, John W., Allen, Christopher C. R., Moody, Thomas S., Gilmore, Brendan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597733/
https://www.ncbi.nlm.nih.gov/pubmed/31123770
http://dx.doi.org/10.1007/s00253-019-09806-y