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PINK1-parkin pathway of mitophagy protects against contrast-induced acute kidney injury via decreasing mitochondrial ROS and NLRP3 inflammasome activation

Contrast-induced acute kidney injury (CI-AKI) occurs in more than 30% of patients after intravenous iodinated contrast media and causes serious complications, including renal failure and mortality. Recent research has demonstrated that routine antioxidant and alkaline therapy failed to show benefits...

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Detalles Bibliográficos
Autores principales: Lin, Qisheng, Li, Shu, Jiang, Na, Shao, Xinghua, Zhang, Minfang, Jin, Haijiao, Zhang, Zhen, Shen, Jianxiao, Zhou, Yijun, Zhou, Wenyan, Gu, Leyi, Lu, Renhua, Ni, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597739/
https://www.ncbi.nlm.nih.gov/pubmed/31229841
http://dx.doi.org/10.1016/j.redox.2019.101254